Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naïve lung adenocarcinoma

Table 1 Allele frequency of common and uncommon EGFR mutations

Patient	Common mutation	Frequency (%)	Uncommon mutation	Frequency (%)	Difference (%)
2294	L858R	6.56	G598 V	6.8	0.24
2312	L858R	13.3	E709G	13.9	0.6
3013	L858R	20.4	E709G	20.4	0
3290	L858R	20.2	E709G	18.4	1.8
1877	G719S	11.8	E709G	12.3	0.5
2233	G719S	30.9	R776H	48.1	17.2
2921	G719A	19.4	D761Y	65.9	46.5

ISSN: 1471-2407