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Fig. 3 | BMC Cancer

Fig. 3

From: MUC16 impacts tumor proliferation and migration through cytoplasmic translocation of P120-catenin in epithelial ovarian cancer cells: an original research

Fig. 3

MUC16 promotes cellular cytoplasmic accumulation of p120ctn without influencing the total expression level of p120ctn in EOC cells. a The total cellular p120ctn protein levels of SKOV3 MUC16 CTD cells are analyzed by western blot. Both bands are p120ctn. b The total RNA levels are confirmed by real-time PCR. Data are shown as the mean ± SEM (n = 3). Nonsignificant (NS). c The total cellular p120ctn protein levels of HO8910 MUC16 KO cells are analyzed by western blot. d The total RNA levels are confirmed by real-time PCR. Data are shown as the mean ± SEM (n = 3). Nonsignificant (NS). Data shown here are representative of 3 independent experiments. e Cytoplasmic or nuclear proteins are extracted and analyzed by western blot

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BMC Cancer

ISSN: 1471-2407

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