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Table 1 Baseline characteristics

From: Fasting plasma glucose is an independent predictor of survival in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy

 

T2DM (n = 56)

Non T2DM (n = 114)

All(n = 170)

p-value

Age,median (range)

66 (49–81)

63 (37–87)

64 (37–87)

0.094

Gender,n (%)

 Male

51 (91.1%)

97 (85.1%)

148 (87%)

 

 Female

5 (8.9%)

17 (14.9%)

22 (13%)

0.337

Smoking history, n (%)

 Current

27 (48.2%)

57 (50%)

84 (49.4%)

 

 Former

24 (42.8%)

51 (44.7%)

75 (44.1%)

 

 Never

3 (5.4%)

4 (3.5%)

7 (4.1%)

 

 Unknown

2 (3.6%)

2 (1.8%)

4 (2.4%)

0.837

ECOG PS, n (%)

 PS 0–1

53 (94.6%)

102 (90.3%)

155 (91.1%)

 

 PS 2

3 (5.4%)

12 (9.7%)

15 (8.9%)

0.331

Histology n (%)

 Adenocarcinoma

9 (16%)

48 (42.1%)

57 (33.5%)

 

 Squamous

29 (51.8%)

43 (37.7%)

72 (42.3%)

 

 NOS

18 (32.2%)

23 (20.2%)

41 (24.2%)

0.003

Stage, n (%)

 IIIA

31 (55.3%)

54 (47.4%)

85 (50%)

 

 IIIB

23 (41.1%)

58 (50.9%)

81 (47.6%)

0.321

Mean baseline glycemia (mmol/L)

9.22 ± 6.35

5.6 ± 1.2

6.75 ± 4.70

< 0.001

Comorbidities

 Any

34 (60.7%)

69 (60.5%)

103 (60.6%)

0.981

 Renal Insufficiency

5 (8.9%)

7 (6.1%)

12 (7.1%)

0.445

 COPD

21 (37.5%)

50 (44%)

71 (41.8%)

0.604

 Cardiovascular

 Hepatopathy

18 (32.1%)

2 (3.6%)

16 (14%)

0 (0%)

34 (20%)

2 (1.2%)

0.003

1.000

Platinum doublet, n (%)

 Cisplatin

27 (48.2%)

77 (67.5%)

104 (61.2%)

 

 Carboplatin

29 (51.7%)

37 (32.5%)

66 (38.8%)

0.019

Total dose of RDT between 60-70Gys

54 (96.4%)

106 (93%)

160 (94%)

0.716

  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status, COPD chronic obstructive pulmonary disease, NOS not otherwise specified, RDT radiotherapy, T2DM type 2 diabetes mellitus