Table 2 Key patient meta-data and derived cell line properties (adapted from Q-Cell database [35])
Cell line | Patient age (years) | Patient Survival (Days) | RB pathway LOF | Cell line doubling time (hours) | XG median survival (days) |
|---|---|---|---|---|---|
BAH1 | 75 | 94 | Yes | 79.5 ± 3.3 | 210 ± 8 |
FPW1 | 68 | 242 | Yes | 48.1 ± 4.7 | 196 ± 4 |
HW1 | 54 | 89 | Yes | 55.8 ± 2.7 | 174 ± 14 |
JK2 | 75 | 178 | Yes | 94.2 ± 4.5 | 147 ± 9 |
MMK1 | 80 | 334 | Yes | 52.4 ± 3.3 | 157 ± 15 |
MN1 | 84 | 36 | Yes | 44.9 ± 1.0 | 258 ± 20 |
PB1 | 57 | 39 | Yes | 79.4 ± 6.3 | 71 ± 1 |
RKI1 | 57 | Alive (7 years) | No | 72.9 ± 5.3 | 248 ± 6 |
RN1 | 56 | 243 | Yes | 37.5 ± 1.9 | 81 ± 2 |
SB2b | 48 | 420 | Yes | 108.7 ± 6.9 | 120 ± 3.3 |
SJH1 | 72 | 45 | Yes | 67.3 ± 4.7 | 148 ± 4 |
WK1 | 77 | 121 | Yes | 46.2 ± 1.0 | 150 ± 2 |