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Table 1 Calcitonin family of receptors [10, 11, 38]

From: Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas

Receptor Heteromers Peptides rank order of potency (human)
CTR CTR sCT ≥ hCT > AMY, αCGRP > AM, intermedin
AMY1 CTR + RAMP1 sCT ≥ AMY ≥ αCGRP > intermedin ≥ hCT > AM
AMY2 CTR + RAMP2 Poorly defined
AMY3 CTR + RAMP3 sCT ≥ AMY > αCGRP > intermedin ≥ hCT > AM
CGRP CLR + RAMP1 αCGRP > AM ≥ intermedin > AMY ≥ sCT
AM1 CLR + RAMP2 AM > intermedin > α-CGRP, AMY > sCT
AM2 CLR + RAMP3 AM ≥ intermedin ≥ α-CGRP > AMY > SCT
  1. Rank order of potency for endogenous peptide ligands for calcitonin receptor family of receptors. sCT Salmon CT, hCT Human CT, AMY1 Amylin 1 receptor, AMY2 Amylin 2 receptor, AMY3 Amylin 3 receptor, CGRP Calcitonin gene related peptide receptor