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Table 3 Univariate and multivariate analyses for overall survival in ED-SCLC patients who received chemotherapy (n = 161)

From: Efficacy and risk of cytotoxic chemotherapy in extensive disease-small cell lung cancer patients with interstitial pneumonia

 

Univariate analysis

Multivariate analysis

Factors

HR

95% CI

P

HR

95% CI

P

IP, yes vs. no

0.87

0.54–1.40

0.56

1.00

0.59–1.70

0.99

Sex, female vs. male

1.08

0.69–1.69

0.73

Excluded

Age, 75 vs. < 75 years

1.24

0.85–1.80

0.26

1.15

0.77–1.71

0.49

ECOG PS 2–4 vs. 0–1

1.61

1.13–2.29

0.01

1.45

0.99–2.12

0.06

Smoking, yes vs. no

1.15

0.50–2.61

0.75

Excluded

Platinum doublet vs AMR

0.60

0.42–0.86

0.005

0.70

0.46–1.06

0.09

  1. Note: IP interstitial pneumonia, PS performance status, AMR amrubicin, HR hazard ratio, 95% CI 95% confidence interval