|
Hepatic metastases
|
|
Mean age at resection + SD Years
|
42 + 7
|
44 + 7
| |
51 + 11
|
50 + 12
| |
63 + 18
|
42 + 4
|
|
Mean interval between primary removal and liver resection + SD Months
|
42 + 20
|
47 + 37
| |
43 + 21
|
46 + 33
| |
28 + 9
|
22 + 9
|
|
Mean number of BCLM diagnosed + SD Distribution
|
2 + 2
|
2 + 2
| |
2 + 2
|
2 + 1
| | | | | |
|
Unilateral
|
5
|
50%
|
4
|
80%
| |
9
|
82%
|
4
|
67%
| |
1
|
50%
|
1
|
100%
|
|
Bilateral
|
5
|
50%
|
1
|
20%
| |
2
|
18%
|
2
|
33%
| |
1
|
50%
|
0
|
0%
|
|
Concomitant extra-hepatic disease
|
|
No
|
10
|
91%
|
4
|
80%
| |
8
|
73%
|
4
|
67%
| |
1
|
50%
|
1
|
100%
|
|
Yes
|
1
|
9%
|
1
|
20%
| |
3
|
27%
|
2
|
33%
| |
1
|
50%
|
0
|
0%
|
|
Chemotherapy before liver resection
| | | | | | | | | | | | | | |
|
No
|
2
|
18%
|
1
|
20%
| |
0
|
0%
|
1
|
17%
| |
0
|
0%
|
0
|
0%
|
|
Yes
|
9
|
82%
|
4
|
80%
| |
11
|
100%
|
5
|
83%
| |
2
|
100%
|
2
|
100%
|
|
Hormonal Therapy before liver resection
|
|
No
|
8
|
73%
|
2
|
40%
| |
2
|
18%
|
2
|
33%
| |
1
|
50%
|
0
|
0%
|
|
Yes
|
3
|
27%
|
3
|
60%
| |
9
|
82%
|
4
|
67%
| |
1
|
50%
|
2
|
100%
|
|
Targeted Therapy before liver resection
|
**
| | | |
|
No
|
7
|
64%
|
4
|
80%
| |
2
|
18%
|
5
|
83%
| |
1
|
50%
|
2
|
100%
|
|
Yes
|
4
|
36%
|
1
|
20%
| |
9
|
82%
|
1
|
17%
| |
1
|
50%
|
0
|
0%
|
|
Histopathological characteristics
|
|
Mean maximum resected tumor size + SD, mm
|
17 + 15
|
33 + 15
|
*
|
21 + 16
|
26 + 12
| |
19 + 8
|
23 + 11
|
|
Resection margin***
|
|
R0
|
8
|
89%
|
3
|
60%
| |
8
|
80%
|
4
|
67%
| |
0
|
0%
|
2
|
100%
|
|
R1
|
1
|
11%
|
2
|
40%
| |
2
|
20%
|
2
|
33%
| |
1
|
100%
|
0
|
0%
|
|
Microscopic intrahepatic invasion
|
|
No
|
6
|
60%
|
1
|
20%
| |
7
|
64%
|
2
|
33%
| |
–
| |
0
|
0%
|
|
Yes
|
4
|
40%
|
4
|
80%
| |
4
|
36%
|
4
|
67%
| |
–
| |
2
| |
|
Cell surface receptors status
|
|
Estrogen
|
|
Negative
|
0
|
0%
|
2
|
40%
| |
4
|
36%
|
2
|
33%
| |
0
|
0%
|
1
|
50%
|
|
Positive
|
8
|
100%
|
3
|
60%
| |
7
|
64%
|
4
|
67%
| |
2
|
100%
|
1
|
50%
|
|
Progesterone
|
|
Negative
|
5
|
63%
|
4
|
80%
| |
6
|
55%
|
2
|
33%
| |
1
|
50%
|
1
|
50%
|
|
Positive
|
3
|
38%
|
1
|
20%
| |
5
|
45%
|
4
|
67%
| |
1
|
50%
|
1
|
50%
|
|
Her2/Neu
|
|
Negative
|
6
|
75%
|
4
|
80%
| |
6
|
60%
|
4
|
67%
| |
0
|
0%
|
2
|
100%
|
|
Positive
|
2
|
25%
|
1
|
20%
| |
4
|
40%
|
2
|
33%
| |
1
|
100%
|
0
|
0%
|
|
Differentiation
|
|
Well differentiated
|
0
|
0%
|
1
|
20%
| |
1
|
14%
|
2
|
40%
| |
1
|
50%
|
0
|
0%
|
|
Moderately differentiated
|
5
|
71%
|
4
|
80%
| |
3
|
43%
|
2
|
40%
| |
0
|
0%
|
1
|
50%
|
|
Poorly differentiated
|
2
|
29%
|
0
|
0%
| |
3
|
43%
|
1
|
20%
| |
1
|
50%
|
1
|
50%
|
