TY - JOUR AU - Weinman, Marcus A. AU - Fischer, Jacob A. AU - Jacobs, Dakota C. AU - Goodall, Cheri P. AU - Bracha, Shay AU - Chappell, Patrick E. PY - 2019 DA - 2019/02/18 TI - Autocrine production of reproductive axis neuropeptides affects proliferation of canine osteosarcoma in vitro JO - BMC Cancer SP - 158 VL - 19 IS - 1 AB - Osteosarcoma strikes hundreds of people each year, of both advanced and younger ages, and is often terminal. Like many tumor types, these bone tumors will frequently undergo a neuroendocrine transition, utilizing autocrine and/or paracrine hormones as growth factors and/or promoters of angiogenesis to facilitate progression and metastasis. While many of these factors and their actions on tumor growth are characterized, some tumor-derived neuropeptides remain unexplored. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-019-5363-4 DO - 10.1186/s12885-019-5363-4 ID - Weinman2019 ER -