TY - JOUR AU - Wang, Junhui AU - Chen, Jianxin PY - 2019 DA - 2019/02/08 TI - Positive response to Icotinib in metastatic lung adenocarcinoma with acquiring EGFR Leu792H mutation after AZD9291 treatment: a case report JO - BMC Cancer SP - 131 VL - 19 IS - 1 AB - Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have been emerged as the standard selection in non-small cell lung cancer (NSCLC) patients with EGFR sensitive mutations. However, primary or acquired resistance to EGFR-TKIs seems inevitable, especially to third-generation TKIs, which has appeared absence of effective solutions so far. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-019-5352-7 DO - 10.1186/s12885-019-5352-7 ID - Wang2019 ER -