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Table 2 Feathers of the next-generation sequencing pipelines used for different sample types

From: Different next-generation sequencing pipelines based detection of tumor DNA in cerebrospinal fluid of lung adenocarcinoma cancer patients with leptomeningeal metastases

  ddCAP ddCAP on tissue cHOPE OncoAim
Number of Genes 10 10 59 59
Targets all exons all exons hotspots hotspots
Enrich method targeted capture targeted capture multiple PCR multiple PCR
DNA input 5~30 ng 50 ng 5~20 ng 10~20 ng
Instruments NextSeq NextSeq NextSeq/miniSeq NextSeq/miniSeq/MiSeq