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Fig. 2 | BMC Cancer

Fig. 2

From: Role of polycyclic aromatic hydrocarbons as a co-factor in human papillomavirus-mediated carcinogenesis

Fig. 2

Dose-dependent effect and synergism of potent PAHs on HPV16E7-transfected BRK cells. Cells were treated with 0.1 μM, 1 μM and 10 of PAHs (a). The degree of dose-response was represented by colony formation index. Synergism of potent PAHs and HPV16E7 on BRK cell transformation (b), cells were treated with HPV16E7 alone; or, 1 μM of PAH alone; or, HPV16E7 together with 1 μM of PAH. Data are the mean ± SEM values obtained from triplicate culture plates per group from three independent experiments. Significant level: *p < 0.05, **p < 0.01, ***p < 0.001. BaP, benzo[a]pyrene; DBA, dibenz[a,h]anthracene; IDP, indeno[1,2,3-cd]pyrene

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