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Table 3 Intracranial and intraspinal tumours among children aged 0–14 years resident in Great Britain, 2001–2010. Numbers of registrations (N), % microscopically verified (MV), rates per million children by age group, age standardised rates (world standard population) (ASR) by sex

From: Incidence of childhood CNS tumours in Britain and variation in rates by definition of malignant behaviour: population-based study

          ASR
ICCC-3    N %MV 0 1–4 5–9 10–14 M F Total
IIIa.1 Ependymoma 291 96.9 2.6 4.4 2.4 1.9 3.1 2.7 2.9
   Unspecified 149 96.0 1.4 2.2 1.4 0.9 1.6 1.4 1.5
   Anaplastic/ependymoblastoma 109 100 1.1 2.1 0.8 0.4 1.2 1.0 1.1
   Papillary 3 66.7 < 0.05 0.1 < 0.05 < 0.05 < 0.05
   Myxopapillary 28 100 0.1 0.2 0.5 0.3 0.2 0.2
   Subependymoma 2 0 < 0.05 < 0.05 < 0.05 < 0.05
IIIa.2 Choroid plexus tumours 111 99.1 6.4 1.5 0.4 0.3 1.3 1.1 1.2
   Papilloma 62 100 3.4 0.8 0.2 0.2 0.8 0.5 0.7
   Atypical papilloma 13 100 1.0 0.1 0.1 0.1 0.2 0.1
   Carcinoma 36 97.2 2.0 0.6 0.1 0.1 0.4 0.4 0.4
IIIb Astrocytoma 1707 81.7 11.1 19.4 16.5 14.7 16.4 16.5 16.5
   Unspecified (optic nerve) 249 7.6 1.7 4.5 2.3 1.0 2.3 2.8 2.5
   Unspecified (other sites) 222 82.9 1.3 2.5 2.3 1.9 2.3 2.0 2.1
   Pilocytic 860 97.0 2.6 9.7 8.5 7.9 8.0 8.4 8.2
   Subependymal giant cell 42 78.6 0.4 0.2 0.4 0.5 0.5 0.3 0.4
   Gliofibroma 1 100 < 0.05 < 0.05 < 0.05
   Protoplasmic 1 100 < 0.05 < 0.05 < 0.05
   Gemistocytic 3 100 0.1 < 0.05 < 0.05
   Fibrillary 29 96.6 0.4 0.1 0.3 0.3 0.2 0.3
   Pleomorphic xanthoastrocytoma 22 100 0.1 0.1 0.4 0.2 0.2 0.2
   Pilomyxoid 38 97.4 1.6 0.5 0.1 0.2 0.4 0.4 0.4
   Anaplastic 93 97.8 1.0 0.6 1.0 0.9 0.9 0.8 0.9
   Glioblastoma 147 97.3 2.6 0.8 1.7 1.3 1.5 1.3 1.4
IIIc.1 Medulloblastoma 522 98.5 3.3 5.9 6.1 3.6 6.5 3.5 5.1
   Unspecified 394 98.0 2.0 3.9 5.0 2.8 5.0 2.5 3.8
   Desmoplastic/nodular/extensive nodularity 84 100 1.1 1.5 0.5 0.5 1.0 0.7 0.9
   Medullomyoblastoma 6 100 0.1 0.1 0.1 0.1
   Large cell/anaplastic 38 100 0.1 0.4 0.5 0.2 0.4 0.3 0.4
IIIc.2 Embryonal CNS tumour NOS 111 95.5 2.7 1.6 0.7 0.7 1.0 1.2 1.1
IIIc.3 Medulloepithelioma/neuroepithelioma 3 100 < 0.05 0.1 < 0.05 < 0.05 < 0.05
IIIc.4 Atypical teratoid/rhabdoid tumour 81 96.3 3.3 1.7 0.2 0.2 0.9 0.9 0.9
IIId.1 Oligodendroglioma 34 100 0.5 0.3 0.3 0.3 0.3 0.3
IIId.2 Mixed and unspecified gliomas 340 22.9 1.0 3.2 4.2 2.8 3.4 3.1 3.2
   Unspecified 318 17.6 1.0 3.0 4.1 2.4 3.2 2.9 3.0
   Mixed 19 100 0.1 0.1 0.4 0.2 0.2 0.2
   Angiocentric glioma 3 100 < 0.05 < 0.05 < 0.05 < 0.05 < 0.05 < 0.05
IIId.3 Other neuroepithelial tumours 23 82.6 0.1 0.1 0.2 0.3 0.2 0.2 0.2
   Gliomatosis cerebri 13 76.9 0.1 0.1 0.1 0.2 0.2 0.1 0.1
   Papillary tumour of the pineal region 5 100 0.1 0.1 < 0.05 0.1 < 0.05
   Astroblastoma 5 80.0 0.1 < 0.05 0.1 < 0.05 0.1 < 0.05
IIIe.1 Pituitary adenoma 67 62.7 0.1 0.2 1.5 0.5 0.6 0.6
IIIe.2 Craniopharyngioma 191 82.7 0.1 1.2 2.2 2.2 1.8 1.7 1.7
IIIe.3 Pineal parenchymal tumours 46 97.8 0.4 0.4 0.4 0.4 0.4 0.4 0.4
   Pineocytoma 4 100 < 0.05 0.1 < 0.05 < 0.05 < 0.05 < 0.05
   Pineoblastoma incl. PTID 42 97.6 0.4 0.4 0.4 0.4 0.4 0.4 0.4
IIIe.4 Mixed glial-neuronal tumours 223 91.5 3.1 1.6 1.9 2.6 2.3 1.8 2.1
   Desmoplastic infantile astrocytoma 21 100 2.1 0.1 0.1 < 0.05 0.3 0.1 0.2
   Dysembryoplastic neuroepithelial tumour 91 86.8 0.1 0.7 0.9 1.1 1.0 0.7 0.8
   Ganglioglioma 96 93.8 0.6 0.7 0.8 1.3 0.9 0.9 0.9
   Central neurocytoma 6 83.3 0.1 0.1 < 0.05 0.1 0.1 0.1
   Papillary glioneuronal tumour 3 100 0.1 < 0.05 < 0.05 < 0.05 < 0.05
   Gangliocytoma 6 100 0.1 0.1 0.1 < 0.05 < 0.05 0.1 0.1
IIIe.5 Meningioma 50 88.0 0.1 0.3 0.3 0.8 0.4 0.5 0.4
IIIf Unspecified tumours 196 19.9 4.5 1.6 1.5 1.9 2.0 1.8 1.9
Xa Germ cell tumours 170 77.6 2.0 0.7 1.0 2.9 1.9 1.1 1.5
   Germinoma 119 76.5 0.1 < 0.05 0.8 2.4 1.3 0.7 1.0
   Other 51 80.4 1.8 0.7 0.1 0.4 0.6 0.4 0.5
   Total 4166 78.8 40.7 44.4 38.6 37.0 42.6 37.5 40.1
  1. Source: National Registry of Childhood Tumours