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Table 5 Univariate and multivariate logistic regression analyses for the uccurence of grade 4 neutropenia

From: The efficacy and toxicity of cabazitaxel for treatment of docetaxel-resistant prostate cancer correlating with the initial doses in Japanese patients

Factors Number (%) Univariate Multivariate
Odds ratio (95% CI) P Odds ratio (95% CI) P
Age (y) > 70 58 (49%) 1.45 (0.68–3.09) 0.340 1.99 (0.85–4.64) 0.113
PS ≥ 1 62 (53%) 0.55 (0.26–1.18) 0.126 0.71 (0.30–1.66) 0.425
DTX cycle< 10 72 (61%) 0.56 (0.26–1.12) 0.146 0.53 (0.22–1.25) 0.148
PEG GCSF use 97 (82%) 0.73 (0.27–2.02) 0.548 0.94 (0.28–3.18) 0.916
Low initial CBZ dose 81 (69%) 0.21 (0.08–0.52) < 0.001* 0.21 (0.08–0.59) 0.002*
  1. PS performance status, DTX docetaxel, PEG:pegfilgrastim, *P < 0.05