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Table 5 Univariate and multivariate logistic regression analyses for the uccurence of grade 4 neutropenia

From: The efficacy and toxicity of cabazitaxel for treatment of docetaxel-resistant prostate cancer correlating with the initial doses in Japanese patients

Factors

Number (%)

Univariate

Multivariate

Odds ratio (95% CI)

P

Odds ratio (95% CI)

P

Age (y) > 70

58 (49%)

1.45 (0.68–3.09)

0.340

1.99 (0.85–4.64)

0.113

PS ≥ 1

62 (53%)

0.55 (0.26–1.18)

0.126

0.71 (0.30–1.66)

0.425

DTX cycle< 10

72 (61%)

0.56 (0.26–1.12)

0.146

0.53 (0.22–1.25)

0.148

PEG GCSF use

97 (82%)

0.73 (0.27–2.02)

0.548

0.94 (0.28–3.18)

0.916

Low initial CBZ dose

81 (69%)

0.21 (0.08–0.52)

< 0.001*

0.21 (0.08–0.59)

0.002*

  1. PS performance status, DTX docetaxel, PEG:pegfilgrastim, *P < 0.05