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Table 4 Novel isoforms. Table of the 20 most significantly differentially expressed novel isoforms

From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

New Isoform ID Closest Known Transcript Locus Treated FPKM Untreated FPKM Log2 Fold Change q_value
XLOC_028771 Fam71f2 6:29275646–29,290,927 8.97 1.06 −3.08 0.00942353
XLOC_000700 Cyb5r1 1:134405743–134,411,742 60.75 7.19 −3.08 0.00942353
XLOC_011906 Grina 15:76246785–76,249,913 131.99 18.55 −2.83 0.00942353
XLOC_008363 Idi1 13:8885500–8,892,451 8.47 55.59 2.72 0.00942353
XLOC_034570 Mcm5 8:75109527–75,128,439 5.52 29.52 2.42 0.00942353
XLOC_004629 Coro6 11:77462410–77,470,484 8.76 1.76 −2.31 0.0478209
XLOC_013221 Tfrc 16:32608919–32,632,794 4.92 23.57 2.26 0.00942353
XLOC_033943 Mki67 7:135689785–135,716,379 1.74 8.18 2.24 0.00942353
XLOC_016993 Fads1 19:10182887–10,196,878 7.66 32.64 2.09 0.0227413
XLOC_010082 Nt5dc2 14:31131073–31,168,641 6.74 26.89 2.0 0.0391793
XLOC_014349 Srrm2 17:23803186–23,824,739 47.42 13.38 −1.83 0.00942353
XLOC_033943 Mki67 7:135689785–135,716,379 4.87 17.22 1.82 0.00942353
XLOC_015979 Lama3 18:12334023–12,584,803 25.18 7.54 −1.74 0.00942353
XLOC_018214 Nelf 2:25054354–25,062,889 20.9 6.28 −1.73 0.0343286
XLOC_011906 Grina 15:76246785–76,249,913 223.87 68.17 −1.72 0.00942353
XLOC_002731 Eea1 10:95940662–96,046,110 15.68 4.81 −1.7 0.0162365
XLOC_022994 Fdps 3:89093587–89,101,967 43.96 142.23 1.69 0.00942353
XLOC_027325 Kntc1 5:123749725–123,821,593 2.24 6.56 1.55 0.00942353
XLOC_023920 Smc2 4:52439242–52,488,364 4.49 13.04 1.54 0.00942353
XLOC_022503 Cenpe 3:135212562–135,273,540 6.55 18.92 1.53 0.0433531
  1. Treated and untreated columns show group average FPKM values. FPKM is a unit of measurement of gene expression (fragments per kilobase of transcript per million mapped reads). Novel transcripts with the highest fold change between groups are shown at the top of the table. The fold change is the log2-fold change in FPKM between the treated and untreated groups. q-values shown are p-values that have been adjusted using the Benjamini-Hochberg false discovery rate (FDR) approach to correct for multiple testing. As a general guide, fold changes with q-values below 0.05 are considered significant