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Table 4 Novel isoforms. Table of the 20 most significantly differentially expressed novel isoforms

From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

New Isoform ID

Closest Known Transcript

Locus

Treated FPKM

Untreated FPKM

Log2 Fold Change

q_value

XLOC_028771

Fam71f2

6:29275646–29,290,927

8.97

1.06

−3.08

0.00942353

XLOC_000700

Cyb5r1

1:134405743–134,411,742

60.75

7.19

−3.08

0.00942353

XLOC_011906

Grina

15:76246785–76,249,913

131.99

18.55

−2.83

0.00942353

XLOC_008363

Idi1

13:8885500–8,892,451

8.47

55.59

2.72

0.00942353

XLOC_034570

Mcm5

8:75109527–75,128,439

5.52

29.52

2.42

0.00942353

XLOC_004629

Coro6

11:77462410–77,470,484

8.76

1.76

−2.31

0.0478209

XLOC_013221

Tfrc

16:32608919–32,632,794

4.92

23.57

2.26

0.00942353

XLOC_033943

Mki67

7:135689785–135,716,379

1.74

8.18

2.24

0.00942353

XLOC_016993

Fads1

19:10182887–10,196,878

7.66

32.64

2.09

0.0227413

XLOC_010082

Nt5dc2

14:31131073–31,168,641

6.74

26.89

2.0

0.0391793

XLOC_014349

Srrm2

17:23803186–23,824,739

47.42

13.38

−1.83

0.00942353

XLOC_033943

Mki67

7:135689785–135,716,379

4.87

17.22

1.82

0.00942353

XLOC_015979

Lama3

18:12334023–12,584,803

25.18

7.54

−1.74

0.00942353

XLOC_018214

Nelf

2:25054354–25,062,889

20.9

6.28

−1.73

0.0343286

XLOC_011906

Grina

15:76246785–76,249,913

223.87

68.17

−1.72

0.00942353

XLOC_002731

Eea1

10:95940662–96,046,110

15.68

4.81

−1.7

0.0162365

XLOC_022994

Fdps

3:89093587–89,101,967

43.96

142.23

1.69

0.00942353

XLOC_027325

Kntc1

5:123749725–123,821,593

2.24

6.56

1.55

0.00942353

XLOC_023920

Smc2

4:52439242–52,488,364

4.49

13.04

1.54

0.00942353

XLOC_022503

Cenpe

3:135212562–135,273,540

6.55

18.92

1.53

0.0433531

  1. Treated and untreated columns show group average FPKM values. FPKM is a unit of measurement of gene expression (fragments per kilobase of transcript per million mapped reads). Novel transcripts with the highest fold change between groups are shown at the top of the table. The fold change is the log2-fold change in FPKM between the treated and untreated groups. q-values shown are p-values that have been adjusted using the Benjamini-Hochberg false discovery rate (FDR) approach to correct for multiple testing. As a general guide, fold changes with q-values below 0.05 are considered significant