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Table 3 Isoforms: Table of the 20 most significantly differentially expressed isoforms (known and novel)

From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

Isoform ID Gene Locus Treated FPKM Untreated FPKM Log2 Fold Change q_value
XLOC_012369 Ywhaz 15:36767848–36,794,547 1.7 80.48 5.57 0.00942353
XLOC_024975 4:150736119–150,739,106 1.64 0.08 −4.42 0.00942353
XLOC_003379 10:79038548–79,046,643 3.34 0.26 −3.67 0.00942353
XLOC_002626 10:82116731–82,122,868 1.48 0.12 −3.62 0.00942353
XLOC_008396 13:14677687–14,682,438 1.26 0.11 −3.5 0.00942353
XLOC_007772 Scin 12:40059768–40,134,228 5.36 0.5 −3.43 0.0391793
XLOC_012908 Krt6a 15:101689931–101,694,307 3.0 31.08 3.37 0.00942353
XLOC_022065 Iqgap3 3:88082044–88,121,048 1.09 10.98 3.33 0.00942353
XLOC_003382 10:79048734–79,059,175 1.67 0.17 −3.3 0.00942353
XLOC_002473 Chchd10 10:75935559–75,940,672 48.82 5.03 −3.28 0.00942353
XLOC_021250 2:148376283–148,382,190 1.74 0.19 −3.16 0.00942353
XLOC_028771 Fam71f2 6:29275646–29,290,927 8.97 1.06 −3.08 0.00942353
XLOC_000700 Cyb5r1 1:134405743–134,411,742 60.75 7.19 −3.08 0.00942353
XLOC_021249 2:148374139–148,376,129 1.33 0.16 −3.01 0.00942353
XLOC_007014 Rrm2 12:24708240–24,714,146 9.74 76.73 2.98 0.00942353
XLOC_004951 Cdc6 11:98907770–98,923,940 1.49 10.97 2.88 0.00942353
XLOC_011906 Grina 15:76246785–76,249,913 131.99 18.55 −2.83 0.00942353
XLOC_034952 Shcbp1 8:4735979–4,779,534 2.93 20.2 2.79 0.00942353
XLOC_032951 Fgf21 7:45613906–45,615,490 3.92 0.58 −2.76 0.00942353
XLOC_005606 Hmmr 11:40701394–40,733,422 3.37 22.21 2.72 0.00942353
  1. Treated and untreated columns show group average FPKM values. FPKM is a unit of measurement of gene expression (fragments per kilobase of transcript per million mapped reads). Isoforms with the highest fold change between groups are shown at the top of the table. The fold change is the log2-fold change in FPKM between the treated and untreated groups. q-values shown are p-values that have been adjusted using the Benjamini-Hochberg false discovery rate (FDR) approach to correct for multiple testing. As a general guide, fold changes with q-values below 0.05 are considered significant