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Table 3 Isoforms: Table of the 20 most significantly differentially expressed isoforms (known and novel)

From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

Isoform ID

Gene

Locus

Treated FPKM

Untreated FPKM

Log2 Fold Change

q_value

XLOC_012369

Ywhaz

15:36767848–36,794,547

1.7

80.48

5.57

0.00942353

XLOC_024975

–

4:150736119–150,739,106

1.64

0.08

−4.42

0.00942353

XLOC_003379

–

10:79038548–79,046,643

3.34

0.26

−3.67

0.00942353

XLOC_002626

–

10:82116731–82,122,868

1.48

0.12

−3.62

0.00942353

XLOC_008396

–

13:14677687–14,682,438

1.26

0.11

−3.5

0.00942353

XLOC_007772

Scin

12:40059768–40,134,228

5.36

0.5

−3.43

0.0391793

XLOC_012908

Krt6a

15:101689931–101,694,307

3.0

31.08

3.37

0.00942353

XLOC_022065

Iqgap3

3:88082044–88,121,048

1.09

10.98

3.33

0.00942353

XLOC_003382

–

10:79048734–79,059,175

1.67

0.17

−3.3

0.00942353

XLOC_002473

Chchd10

10:75935559–75,940,672

48.82

5.03

−3.28

0.00942353

XLOC_021250

–

2:148376283–148,382,190

1.74

0.19

−3.16

0.00942353

XLOC_028771

Fam71f2

6:29275646–29,290,927

8.97

1.06

−3.08

0.00942353

XLOC_000700

Cyb5r1

1:134405743–134,411,742

60.75

7.19

−3.08

0.00942353

XLOC_021249

–

2:148374139–148,376,129

1.33

0.16

−3.01

0.00942353

XLOC_007014

Rrm2

12:24708240–24,714,146

9.74

76.73

2.98

0.00942353

XLOC_004951

Cdc6

11:98907770–98,923,940

1.49

10.97

2.88

0.00942353

XLOC_011906

Grina

15:76246785–76,249,913

131.99

18.55

−2.83

0.00942353

XLOC_034952

Shcbp1

8:4735979–4,779,534

2.93

20.2

2.79

0.00942353

XLOC_032951

Fgf21

7:45613906–45,615,490

3.92

0.58

−2.76

0.00942353

XLOC_005606

Hmmr

11:40701394–40,733,422

3.37

22.21

2.72

0.00942353

  1. Treated and untreated columns show group average FPKM values. FPKM is a unit of measurement of gene expression (fragments per kilobase of transcript per million mapped reads). Isoforms with the highest fold change between groups are shown at the top of the table. The fold change is the log2-fold change in FPKM between the treated and untreated groups. q-values shown are p-values that have been adjusted using the Benjamini-Hochberg false discovery rate (FDR) approach to correct for multiple testing. As a general guide, fold changes with q-values below 0.05 are considered significant
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BMC Cancer

ISSN: 1471-2407

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