Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

Table 1 The 20 most significantly differentially expressed genes

Gene ID	Gene	Locus	Treated FPKM	Untreated FPKM	Log² Fold Change	q_value
XLOC_001070	Mir29b2, Mir29c, mmu-mir-29b-2	1:194938820–195,037,908	426.25	4.19	−6.67	0.00215219
XLOC_034022	H19, Mir675	7:142575528–142,578,143	20.65	568.45	4.78	0.00215219
XLOC_002346	Gp49a, Lilrb4	10:51480631–51,496,613	24.53	0.97	−4.66	0.00215219
XLOC_024975	–	4:150736119–150,739,106	1.64	0.08	−4.42	0.00215219
XLOC_026432	Car6	4:150187014–150,201,332	3.34	0.18	−4.21	0.00215219
XLOC_036797	Angptl6	9:20868641–20,879,727	28.72	2.07	−3.79	0.00215219
XLOC_013580	AC115005.1, Gm7541	16:8622332–8,624,782	7.85	0.6	−3.7	0.00215219
XLOC_003379	–	10:79038548–79,046,643	3.34	0.26	−3.67	0.00215219
XLOC_002626	–	10:82116731–82,122,868	1.48	0.12	−3.62	0.00215219
XLOC_003263	Col13a1	10:61838235–61,979,108	0.78	0.06	−3.61	0.00382174
XLOC_037321	AC163666.1, SNORD50	9:88595218–88,599,516	1.18	13.74	3,54	0.00215219
XLOC_028771	Fam71f2	6:29275646–29,290,927	28.77	2.54	−3.5	0.00215219
XLOC_008396	–	13:14677687–14,682,438	1.26	0.11	−3.5	0.00215219
XLOC_008544	Dcdc2a	13:25056003–25,210,706	1.56	0.14	−3.44	0.023298
XLOC_012908	Krt6a	15:101689931–101,694,307	3.0	31.08	3.37	0.00215219
XLOC_012225	Soat2	15:102150517–102,163,474	10.76	1.04	−3.37	0.00539903
XLOC_019276	Gm14047	2:129364569–129,376,154	6.63	0.67	−3.31	0.0173413
XLOC_003382	–	10:79048734–79,059,175	1.67	0.17	−3.3	0.00215219
XLOC_002473	Chchd10	10:75935559–75,940,672	62.53	6.36	−3.3	0.00215219
XLOC_036264	2810417H13Rik	9:65828929–65,908,794	4.88	47.75	3.29	0.0105894

Treated and untreated columns show group average FPKM values. FPKM is a unit of measurement of gene expression (fragments per kilobase of transcript per million mapped reads). Transcripts with the highest fold change between groups are shown at the top of the table. The fold change is the log2-fold change of FPKM between the treated and untreated groups. q-values shown are p-values that have been adjusted using the Benjamini-Hochberg false discovery rate (FDR) approach to correct for multiple testing. As a general guide, fold changes with q-values below 0.05 may be considered significant

ISSN: 1471-2407