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Fig. 8 | BMC Cancer

Fig. 8

From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

Fig. 8

Invasion (a) and Migration (b) studies in mouse lung non-metastatic KW-634 cells; invasion assay in metastatic 821-T4 cells (c), and migration in metastatic 821-LN cells (d) (blue control, green miR-200c treatment, red Nano miR-200c treatment). Protein assay using the ActivSignal IPAD Platform to help understand the pathway activation/inhibition profiles of cells by assessing the signaling pathways in each sample of mouse lung non-metastatic KW-634 cells (e). The IPAD assay allows direct measurement of the expression and modification of components of signaling pathways. Hippo pathway activity (e1), Cell cycle regulation (e2) and EMT (e3)

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