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Fig. 5 | BMC Cancer

Fig. 5

From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells

Fig. 5

Endogenous expression of direct targets of miR-200c in mouse lung non-metastatic (KW-634, blue bars) and metastatic (821-T4, violet bars; 821-LN, green bars) cell lines, showing the various roles and effectiveness of our Nano encapsulation of miR-200c after each treatment with 50 nM miR-200c and nano-miR-200c. a- Nkx2.1 expression levels were maintained following treatment with Nano miR-200c in non-metastatic KW-634 and were elevated in metastatic 821-T4, while they were almost undetectable in metastatic 821-LN. b- Six4 showed significant expression in the cell lines treated with miR-200c and Nano miR-200c, and c- Myb expression was considerably affected by Nano miR-200c treatment in all lines

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