Fig. 4

CD133 expression signature levels and immunohistochemistry (IHC)-based CD133 positivities in GC primary cases. a Eighteen GC primary cases were sorted in order of the expression signature level of CD133-up (the top row in the heat map). A barplot shows the level of IHC score (y-axis) with IHC-based CD133+ and CD133- primary cases (red and blue, respectively; upper panel). A heatmap shows the level of signature levels examined for 18 primary GC cases (below). b The signal-to-noise ratios (SNR) estimated from the cell lines (y-axis) and primary cases (x-axis) are shown in a scatter plot. No significant correlation was observed. c The correlation level with stromal signatures are shown for IHC score, PROM1 expression and CD133-up signature levels, respectively