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Table 1 Number of regulated genes in skin of mice 2 weeks after administration of CTX with or without M30

From: Genetic analysis of a novel antioxidant multi-target iron chelator, M30 protecting against chemotherapy-induced alopecia in mice

Condition Fold-change P value Mice (n) Regulated genes (no.)
Total Up Down
CTX/Normal > 1.5 < 0.05 Normala (3), CTXb (3) 7722 3422 4300
MC/Normal > 1.5 < 0.05 Normal (3), MCc (3) 1148 866 282
MC/CTX > 1.5 < 0.05 CTX (3), MC (3) 2753 1715 1038
Condition 1 > 1.5 (CTX/Normal) & < 0.666 (MC/CTX) < 0.05 Normal (3), CTX (3), MC (3) 644   
Condition 2 < 0.666 (CTX/Normal) & > 1.5 (MC/CTX) < 0.05 Normal (3), CTX (3), MC (3) 241   
  1. aNormal is normal mice: bCTX is cyclophosphamide-treated mice: cMC is M30-supplemented cyclophosphamide-treated mice