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Fig. 5 | BMC Cancer

Fig. 5

From: VEGFR2 promotes tumorigenesis and metastasis in a pro-angiogenic-independent way in gastric cancer

Fig. 5

The effect of VEGFR2 on VTN expression. a & b Real-time PCR and Western blot analysis of relative levels of VTN in MKN-45 cells after VEGFR2 knockdown. c & d Real-time PCR and Western blot analysis of relative levels of VTN in SCH cells after VEGFR2 overexpression. e & f Real-time PCR and Western blot analysis of relative levels of VTN in a panel of gastric cancer cell lines and immortalized normal human gastric mucosal epithelial cell line GES-1. g & h IHC staining analysis of VTN in MKN-45 xenograft tumors. i & j IHC staining analysis of VTN in SCH xenograft tumors. k Representative images of anti-VTN staining in human gastric cancer tissues. l Relationship between expressions of VEGFR2 and VTN in human gastric cancer tissues. **P < 0.01, significant differences vs. the respective control groups

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