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Table 2 Correlation between TIL subtype infiltration at the TC and the ITF

From: Dissimilar patterns of tumor-infiltrating immune cells at the invasive tumor front and tumor center are associated with response to neoadjuvant chemotherapy in primary breast cancer

A: Correlation TILs ITF-ITF
ITF
ITF   TILs CD3 CD20 CD68 CD4 CD8
TILs   7.92 E-20 (0.83) 3.50 E-7 (0.68) 0.2508 (0.32) 0.0224 (0.54) 0.0002 (0.51)
CD3 7.92 E-20 (0.83)   1.39 E-5 (0.64) 1 (0.23) 5.35 E-5 (0.63) 0.0054 (0.57)
CD20 3.50 E-7 (0.68) 1.39 E-5 (0.64)   1 (−0.02) 1 (0.26) 0.0178 (0.40)
CD68 0.2508 (0.32) 1 (0.23) 1 (−0.02)   0.3366 (0.32) 1 (0.01)
CD4 0.0224 (0.54) 5.35 E-5 (0.63) 1 (0.26) 0.3366 (0.32)   0.0112 (0.42)
CD8 0.0002 (0.51) 0.0054 (0.57) 0.0178 (0.40) 1 (0.01) 0.0112 (0.42)  
B: Correlation TILs TC-TC
TC
TC   TILs CD3 CD20 CD68 CD4 CD8
TILs   6.6 E-17 (0.78) 0.0018 (0.44) 0.0011 (0.45) 0.0086 (0.4) 5.08 E-5 (0.61)
CD3 6.6 E-17 (0.78)   7.26 E-5 (0.5) 1 (0.1) 0.0290 (0.37) 2.05 E-7 (0.67)
CD20 0.0018 (0.44) 7.26 E-5 (0.5)   1 (−0.02) 1 (0.21) 0.0051 (0.55)
CD68 0.0011 (0.45) 1 (0.1) 1 (−0.02)   0.099 (0.34) 1 (0.1)
CD4 0.0086 (0.4) 0.0290 (0.37) 1 (0.21) 0.099 (0.34)   0.0568 (0.36)
CD8 5.08 E-5 (0.61) 2.05 E-7 (0.67) 0.0051 (0.55) 1 (0.1) 0.0568 (0.36)  
C: Correlation TILs ITF-TC
ITF
TC   TILs CD3 CD20 CD68 CD4 CD8
TILs 0.0005 (0.48) 0.0003 (0.49) 0.0251 (0.39) 0.924 (0.27) 0.0023 (0.45) 0.1254 (0.35)
CD3 0.0013 (0.46) 0.0005 (0.49) 0.0013 (0.46) 1 (0.08) 0.0011 (0.48) 0.0086 (0.42)
CD20 1 (0.12) 1 (0.08) 1 (0.23) 1 (−0.19) 1 (0.08) 1 (0.08)
CD68 1 (0.22) 1 (0.23) 1 (0.03) 0.0026 (0.45) 0.0653 (0.37) 1 (0.03)
CD4 1 (0.1) 1 (0.16) 1 (0.05) 1 (0.25) 0.0012 (0.47) 1 (0.12)
CD8 1 (0.2) 1 (0.24) 0.495 (0.30) 1 (−0.09) 1 (0.21) 1 (0.2)
  1. Bonferroni adjusted p-values (rho)
  2. (A) ITF-ITF, (B) TC-TC and (C) ITF-TC. Results are given as Bonferroni adjusted p-values (rho). All bold values are significant p-values with "rho" in brackets