Prognostic value of adipose tissue and muscle mass in advanced colorectal cancer: a post hoc analysis of two non-randomized phase II trials

Table 2 Test for heterogeneity comparing SoMore and RegARd-C

	SoMore	RegARd-c	P-value Test heterogeneity
	Hazard ratio (95% CI)	Hazard ratio (95% CI)	P-value Test heterogeneity
Muscle index (low vs high)	1.55 (1.00 to 2.38)	1.86 (1.28 to 2.72)	0.53
Muscle density (low vs high)	0.74 (0.48 to 1.14)	1.12 (0.78 to 1.63)	0.15
Subcutaneaous fat index (low vs high)	1.08 (0.70 to 1.66)	1.81 (1.24 to 2.64)	0.08
Subcutaneous fat density (low vs high)	0.64 (0.41 to 0.98)	0.53 (0.37 to 0.77)	0.52
Visceral fat index (low vs high)	1.21 (0.79 to 1.86)	1.59 (1.09 to 2.31)	0.35
Visceral fat density (low vs high)	0.60 (0.39 to 0.92)	0.42 (0.28 to 0.61)	0.23

Hazard ratio for OS were calculated for muscle index, muscle density, subcutaneous fat index, subcutaneous fat density, visceral fat index and visceral fat density comparing patients above and below the gender-specific median in each dataset. A test for heterogeneity comparing the two datasets for each body composition parameter was then performed and did not reach statistical significance

ISSN: 1471-2407