Table 2 Top mutated genes in GENIE
Gene | Variants observed |
|---|---|
TP53 | 8083 |
KRAS | 2811 |
PIK3CA | 2693 |
APC | 2674 |
KMT2D | 1980 |
ARID1A | 1494 |
PTEN | 1313 |
EGFR | 1212 |
ATM | 1202 |
NF1 | 1122 |
BRAF | 1116 |
BRCA2 | 949 |
NOTCH1 | 924 |
RB1 | 917 |
ATRX | 887 |
SETD2 | 845 |
CREBBP | 840 |
CDKN2A | 788 |
ERBB4 | 740 |
KMT2A | 739 |
SMAD4 | 733 |
ARID1B | 719 |
SMARCA4 | 696 |
ROS1 | 688 |
FBXW7 | 687 |
EP300 | 669 |
ARID2 | 649 |
PTPRD | 647 |
TET2 | 642 |
DNAPK | 639 |
Others | 70,732 |