Table 1 Hall of fame variants that appear in over 100 samples

KRAS

p.Gly12Asp

c.35G > A

BRAF

p.Val600Glu

c.1799 T > A

KRAS

p.Gly12Val

c.35G > T

PIK3CA

p.Glu545Lys

c.1633G > A

PIK3CA

p.His1047Arg

c.3140A > G

KRAS

p.Gly12Cys

c.34G > T

TP53

p.Arg175His

c.524G > A

PIK3CA

p.Glu542Lys

c.1624G > A

IDH1

p.Arg132His

c.395G > A

KRAS

p.Gly13Asp

c.38G > A

TP53

p.Arg273His

c.818G > A

TP53

p.Arg273Cys

c.817C > T

TP53

p.Arg248Gln

c.743G > A

TP53

p.Arg248Trp

c.742C > T

TP53

p.Arg282Trp

c.844C > T

TP53

p.Arg213*

c.637C > T

NRAS

p.Gln61Arg

c.182A > G

EGFR

p.Leu858Arg

c.2573 T > G

EGFR

p.Glu746_Ala750del

c.2236_2250delGAATTAAGAGAAGCA

AKT1

p.Glu17Lys

c.49G > A

KRAS

p.Gly12Ala

c.35G > C

TP53

p.Arg342*

c.1024C > T

NRAS

p.Gln61Lys

c.181C > A

TP53

p.Arg196*

c.586C > T

IDH1

p.Arg132Cys

c.394C > T

KRAS

p.Gln61His

c.183A > T

TP53

p.Tyr220Cys

c.659A > G

APC

p.Arg1450*

c.4348C > T

APC

p.Arg876*

c.2626C > T

FGFR3

p.Ser249Cys

c.746C > G