Table 4 Tumors present in the families of patients with mutations in TP53
Tumor | 1st degree relatives | 2nd degree relatives | 3rd degree relatives | Total | Ranges of ages at diagnosis |
|---|---|---|---|---|---|
Breast | 1 | 0 | 0 | 1 | < 35 |
Lung | 1 | 2 | 1 | 4 | 25–70 |
Prostate | 0 | 0 | 1 | 1 | > 70 |
Testicular | 0 | 0 | 1 | 1 | < 30 |
Leukemia | 0 | 1 | 1 | 2 | 10–30 |
CRC | 1 | 0 | 1 | 2 | 40–60 |
Osteosarcoma | 1 | 0 | 0 | 1 | < 20 |
Brain | 2 | 0 | 0 | 2 | 5–50 |
NS Tumor | 0 | 1 | 0 | 1 | < 40 |
Cervical | 0 | 1 | 0 | 1 | < 60 |