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Table 4 Tumors present in the families of patients with mutations in TP53

From: Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population

Tumor 1st degree relatives 2nd degree relatives 3rd degree relatives Total Ranges of ages at diagnosis
Breast 1 0 0 1 <  35
Lung 1 2 1 4 25–70
Prostate 0 0 1 1 > 70
Testicular 0 0 1 1 < 30
Leukemia 0 1 1 2 10–30
CRC 1 0 1 2 40–60
Osteosarcoma 1 0 0 1 < 20
Brain 2 0 0 2 5–50
NS Tumor 0 1 0 1 < 40
Cervical 0 1 0 1 < 60
  1. NS Not specified