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Table 2 Comparison of miRNA expression in cervical exfoliated cells between consistent LSIL/CIN1 group and missed high-grade lesion group

From: MiRNA detection in cervical exfoliated cells for missed high-grade lesions in women with LSIL/CIN1 diagnosis after colposcopy-guided biopsy

Variable

Consistent LSIL/CIN1 group (n = 150)Median (IQR)

Missed high-grade lesion group (n = 27)Median (IQR)

p

miRNA195 (×10−5)

1.81(1.30–2.25)

0.72(0.53–0.96)

<  0.001

miRNA424 (×10−5)

1.50(0.48–3.87)

1.08(0.55–2.98)

0.712

miRNA375 (×10−3)

6.67(3.39–13.66)

4.27(2.82–16.66)

0.547

miRNA218 (×10−5)

2.60(1.14–6.34)

2.51(1.05–9.17)

0.775

miRNA34a (×10−4)

4.38(1.69–9.48)

3.58(1.64–10.10)

0.664

miRNA29a (×10−5)

1.975(1.46–2.59)

0.86(0.63–1.03)

<  0.001

miRNA16–2(× 10−4)

0.494(0.38–0.60)

0.638(0.54–0.73)

<  0.001

miRNA20a (× 10− 4)

0.5005(0.33–0.68)

0.861(0.74–0.98)

< 0.001

  1. LSIL/CIN1: Low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1
  2. IQR Interquartile range. P value in boldface is less than 0.05 and considered statistically significant