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Table 2 Comparison of miRNA expression in cervical exfoliated cells between consistent LSIL/CIN1 group and missed high-grade lesion group

From: MiRNA detection in cervical exfoliated cells for missed high-grade lesions in women with LSIL/CIN1 diagnosis after colposcopy-guided biopsy

Variable Consistent LSIL/CIN1 group (n = 150)Median (IQR) Missed high-grade lesion group (n = 27)Median (IQR) p
miRNA195 (×10−5) 1.81(1.30–2.25) 0.72(0.53–0.96) <  0.001
miRNA424 (×10−5) 1.50(0.48–3.87) 1.08(0.55–2.98) 0.712
miRNA375 (×10−3) 6.67(3.39–13.66) 4.27(2.82–16.66) 0.547
miRNA218 (×10−5) 2.60(1.14–6.34) 2.51(1.05–9.17) 0.775
miRNA34a (×10−4) 4.38(1.69–9.48) 3.58(1.64–10.10) 0.664
miRNA29a (×10−5) 1.975(1.46–2.59) 0.86(0.63–1.03) <  0.001
miRNA16–2(× 10−4) 0.494(0.38–0.60) 0.638(0.54–0.73) <  0.001
miRNA20a (× 10− 4) 0.5005(0.33–0.68) 0.861(0.74–0.98) < 0.001
  1. LSIL/CIN1: Low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1
  2. IQR Interquartile range. P value in boldface is less than 0.05 and considered statistically significant
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