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Table 1 Characteristics of the study subjects

From: MiRNA detection in cervical exfoliated cells for missed high-grade lesions in women with LSIL/CIN1 diagnosis after colposcopy-guided biopsy

 

Histology

P value

Consistent LSIL/CIN1 group (n = 150)

Missed high-grade lesion group (n = 27)

Age (years)

 Mean (SD)

39.4 (±6.6)

39.8 (±7.1)

 

  < 40

68 (45.33%)

12 (44.44%)

0.932

  ≥ 40

82 (54.67%)

15 (55.56%)

 

HR-HPV

 Positive

130 (86.67%)

27 (100%)

0.044

 Negative

20 (13.33%)

0 (0%)

 

HPV genotyping

 Positive of HPV16,18

35 (23.33%)

8 (29.63%)

0.483

 Negative of HPV16,18

115 (76.67%)

19 (70.37%)

 

Pap test

 ASC-H-

137 (91.33%)

21 (77.78%)

0.036

 ASC-H+

13 (8.67%)

6 (22.22%)

 

Smoking

 Non-smoker

105 (70%)

21 (77.78%)

0.411

 Smoker*

45 (30%)

6 (22.22%)

 

Number of lifetime sexual partners

 1

123 (82%)

21 (77.78%)

0.604

 2+

27 (18%)

6 (22.22%)

 

Age at first sexual intercourse (years)

  < 20

40 (26.67%)

7 (25.93%)

0.474

 20–24

90 (60%)

14 (51.85%)

 

  > 24

20 (13.33%)

6 (22.22%)

 
  1. The P value was calculated by the Pearson Chi-Square test
  2. LSIL/CIN1: Low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1
  3. SD Standard Deviation
  4. HPV Human papillomavirus
  5. HR-HPV High-risk human papillomavirus
  6. ASC-H+ equal or greater than atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion
  7. *including smokers and second-hand smoker subjects