Skip to main content

Table 1 Characteristics of the study subjects

From: MiRNA detection in cervical exfoliated cells for missed high-grade lesions in women with LSIL/CIN1 diagnosis after colposcopy-guided biopsy

  Histology P value
Consistent LSIL/CIN1 group (n = 150) Missed high-grade lesion group (n = 27)
Age (years)
 Mean (SD) 39.4 (±6.6) 39.8 (±7.1)  
  < 40 68 (45.33%) 12 (44.44%) 0.932
  ≥ 40 82 (54.67%) 15 (55.56%)  
HR-HPV
 Positive 130 (86.67%) 27 (100%) 0.044
 Negative 20 (13.33%) 0 (0%)  
HPV genotyping
 Positive of HPV16,18 35 (23.33%) 8 (29.63%) 0.483
 Negative of HPV16,18 115 (76.67%) 19 (70.37%)  
Pap test
 ASC-H- 137 (91.33%) 21 (77.78%) 0.036
 ASC-H+ 13 (8.67%) 6 (22.22%)  
Smoking
 Non-smoker 105 (70%) 21 (77.78%) 0.411
 Smoker* 45 (30%) 6 (22.22%)  
Number of lifetime sexual partners
 1 123 (82%) 21 (77.78%) 0.604
 2+ 27 (18%) 6 (22.22%)  
Age at first sexual intercourse (years)
  < 20 40 (26.67%) 7 (25.93%) 0.474
 20–24 90 (60%) 14 (51.85%)  
  > 24 20 (13.33%) 6 (22.22%)  
  1. The P value was calculated by the Pearson Chi-Square test
  2. LSIL/CIN1: Low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1
  3. SD Standard Deviation
  4. HPV Human papillomavirus
  5. HR-HPV High-risk human papillomavirus
  6. ASC-H+ equal or greater than atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion
  7. *including smokers and second-hand smoker subjects