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Fig. 3 | BMC Cancer

Fig. 3

From: Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome

Fig. 3

Migration assessed by wound healing. Overexpression of Fascin-1 in SaOS-2 (a) or in 143B (b) OS cells increases significantly the migration ability. Similarly, silencing of Fascin-1 slightly decreased the migratory rate of SaOS-2 (a) and 143B (b) cells. Results are the mean ± SEM of at least three independent experiments. (c) Zymography analysis showing increased MMP-9 activity in SaOS-2/Fascin-1 (left panel) and in 143B/Fascin-1 (right panel) in comparison to control SaOS-1/EV and 143B/EV cells respectively. Results are the mean ± SEM of three independent experiments

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