Fig. 2

CORT feeding increases plasma CORT of AOM/DSS-induced CRC mice. The scheme shows model mice recovered for 7 days after the last cycle of DSS treatment and then undertook with vehicle treatment (VT, 0.5% ethanol, number = 10) or CORT treatment (CT,50 mg/L, number = 11) randomly for 31 days (a). Methodology workflow of the study (b). Survival rate of CT mice (number = 11) and VT mice (number = 10) (c). Plasma CORT of CT mice (number = 8) compared with VT mice (number = 8) (d). Data expressed as mean ± SD. *P < 0.05, **P < 0.01 by unpaired t-test analysis. CORT corticosterone, CT CORT treatment, VT vehicle treatment