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Table 4 Uni- and multivariable analysis of RFS and OAS for various high risk subgroups of pN1-patients stratified by LN ratio for pN1-patients with 10 ≤ or more than 10 LN excised

From: Does the number of removed axillary lymphnodes in high risk breast cancer patients influence the survival?

Number of excised LN

LN ratio

univariate

multivariatea

≤10

RFS

P < 0.001; HR = 5,47; (95% CI 2,30-13,4)

P < 0.001; HR = 5,34; (95% CI 2,24-12,70)

OAS

P < 0.001; HR = 4,30; (95% CI 2,28-8,10)

P = 0.001; HR = 2,99; (95% CI 1,50-5,56)

> 10

RFS

P < 0.001; HR = 6,45; (95% CI 4,74-8,78)

P < 0.001; HR = 4,57; (95% CI 3,29-6,36)

OAS

P < 0.001; HR = 6,29; (95% CI 4,77-8,30)

P < 0.001; HR = 3,40; (95% CI 2,53-4,56)

  1. Uni- and multivariate analysis of RFS and OAS stratified by LN ratio (as continuous variable) for pN1-patients with 10 and less LN versus more than 10 LN excised; aadjusted by age, tumor size, intrinsic sub types and guideline adherent adjuvant systemic therapy