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Table 2 Recurrence free and Overall survival of pN+ patients by number of excised lymph nodes (10 ≤ LN < 10) and adjusted by age, tumor size, intrinsic sub types and guideline adherent adjuvant systemic therapy

From: Does the number of removed axillary lymphnodes in high risk breast cancer patients influence the survival?

 

Recurrence free survival

Overall survival

   

95,0% CI for HR

  

95,0% CI for HR

 

Sig.

HR

Lower

Upper

Sig.

HR

Lower

Upper

Age at primary diagnosis

0.248

1.00

0.99

1.00

< 0.001

1.05

1.04

1.06

Tumor size (mm)

< 0.001

1.01

1.00

1.01

< 0.001

1.01

1.00

1.01

Intrinsic sub types

< 0.001

   

< 0.001

   

Luminal B/HER2-

< 0.001

2.01

1.54

2.61

< 0.001

1.72

1.38

2.15

Luminal B/HER2+

0.003

1.61

1.18

2.21

0.010

1.42

1.09

1.86

TNT

< 0.001

3.55

2.63

4.79

< 0.001

2.96

2.27

3.87

HER2 overexpressing

< 0.001

3.35

2.39

4.70

< 0.001

2.07

1.47

2.91

Guideline-adherent hormonal therapy

< 0.001

1.91

1.43

2.55

< 0.001

2.00

1.59

2.52

Guideline-adherent chemotherapy

< 0.001

1.84

1.46

2.31

< 0.001

1.83

1.51

2.22

  1. The most important parameters for recurrence free survival are intrinsic sub types, tumor size and guideline adherent chemo- and hormonal therapy (Wald statistics)