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Table 2 Recurrence free and Overall survival of pN+ patients by number of excised lymph nodes (10 ≤ LN < 10) and adjusted by age, tumor size, intrinsic sub types and guideline adherent adjuvant systemic therapy

From: Does the number of removed axillary lymphnodes in high risk breast cancer patients influence the survival?

  Recurrence free survival Overall survival
    95,0% CI for HR    95,0% CI for HR
  Sig. HR Lower Upper Sig. HR Lower Upper
Age at primary diagnosis 0.248 1.00 0.99 1.00 < 0.001 1.05 1.04 1.06
Tumor size (mm) < 0.001 1.01 1.00 1.01 < 0.001 1.01 1.00 1.01
Intrinsic sub types < 0.001     < 0.001    
Luminal B/HER2- < 0.001 2.01 1.54 2.61 < 0.001 1.72 1.38 2.15
Luminal B/HER2+ 0.003 1.61 1.18 2.21 0.010 1.42 1.09 1.86
TNT < 0.001 3.55 2.63 4.79 < 0.001 2.96 2.27 3.87
HER2 overexpressing < 0.001 3.35 2.39 4.70 < 0.001 2.07 1.47 2.91
Guideline-adherent hormonal therapy < 0.001 1.91 1.43 2.55 < 0.001 2.00 1.59 2.52
Guideline-adherent chemotherapy < 0.001 1.84 1.46 2.31 < 0.001 1.83 1.51 2.22
  1. The most important parameters for recurrence free survival are intrinsic sub types, tumor size and guideline adherent chemo- and hormonal therapy (Wald statistics)