Fig. 2
From: CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer
Differential mRNA gene expression analysis between matched primary and metastatic tumors in “Pilot-TNBC” patients (n = 8). a Heatmap illustrating mRNA expression fold changes (metastatic versus primary, > 1.5) of 455 differentially expressed genes. Three hundred seventeen genes were upregulated and 138 genes were downregulated in metastatic disease versus primary disease. b Heatmap highlighting the eight putative cancer driver genes that were upregulated in metastatic TNBCs: CCNE1, TPX2, GSK3B, CEP76, SYK, JAK2, ELF3 and FANCL