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Table 6 Associations between expression level of TGF-β, IL-17, IL-6, IL-1, TNF-α, NF-κB, ROS, RNS, BRCA1 and BRCA2 with breast cancer and presence of HPV

From: Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins

Expression level

Breast Cancer

Presence of HPV

Correlation Coefficient

Adjusted P-value*

Correlation Coefficient

Adjusted P-value*

TGF-β

0.608

0.0016

0.877

< 0.001

IL-17

0.618

0.0087

0.953

< 0.001

IL-6

0.464

0.0016

0.959

< 0.001

IL-1

0.497

0.0410

0.949

< 0.001

TNF-α

0.602

0.0071

0.971

< 0.001

NF-κB

0.418

0.0155

0.953

< 0.001

ROS

0.613

< 0.001

0.958

< 0.001

RNS

0.633

< 0.001

0.956

< 0.001

BRCA1

0.831

< 0.001

0.797

< 0.001

BRCA2

0.736

< 0.001

0.952

< 0.001

  1. * FDR correction for multiple comparisons by Benjamini-Hochberg method. Eta-squared considered as an effect size of correlation