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Table 5 Comparison expressions level of TGF-β, IL-17, IL-6, IL-1, TNF-α, NF-κB, ROS, RNS, BRCA1 and BRCA2 in breast cancer, control samples, positive HPV, and negative HPV samples

From: Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins

Expression level Breast Cancer (N = 72) Control (N = 31) Fold Change Adjusted P-value* HPV positive(N = 40) HPV negative(N = 63) Fold Change Adjusted P-value*
TGF-β 12.40 ± 9.11 5.29 ± 3.68 2.34 0.0013 18.65 ± 7.53 4.94 ± 3.06 3.75 0.001
IL-17 12.61 ± 9.46 4.97 ± 4.29 2.54 0.0013 20.05 ± 6.28 4.13 ± 3.33 4.85 0.001
IL-6 9.32 ± 7.27 3.97 ± 3.29 2.35 0.0013 14.30 ± 5.58 3.52 ± 3.22 4.06 0.001
IL-1 8.90 ± 6.21 6.10 ± 4.48 1.46 0.0103 14.65 ± 5.06 3.87 ± 2.30 3.78 0.001
TNF-α 9.40 ± 7.56 4.77 ± 3.28 1.97 0.0013 15.83 ± 6.33 3.05 ± 3.01 5.19 0.001
NF-κB 9.26 ± 7.67 5.48 ± 4.91 1.69 0.0290 14.75 ± 5.97 3.92 ± 3.51 3.76 0.001
ROS 10.08 ± 8.87 3.35 ± 3.06 3.01 0.0013 16.38 ± 7.29 2.78 ± 2.47 5.89 < 0.001
RNS 11.32 ± 9.84 3.94 ± 2.88 2.87 0.0013 17.82 ± 8.82 3.56 ± 2.83 5.01 < 0.001
BRCA1 9.58 ± 5.35 14.45 ± 4.58 0.66 0.0013 8.32 ± 4.43 12.77 ± 5.58 0.65 < 0.001
BRCA2 7.23 ± 3.84 12.66 ± 4.03 0.57 0.0013 5.15 ± 1.92 11.22 ± 3.79 0.46 < 0.001
  1. * FDR correction for multiple comparisons by Benjamini-Hochberg method