From: Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins
Characteristics | HPV+ | HPV- | P-value | OR (95% CI) | |
---|---|---|---|---|---|
Age (Year) | 48.00 ± 11.11 | 49.46 ± 9.99 | 0.49 | – | |
Stage of Cancer | I | 4 (11.5%) | 7 (18.9%) | Ref. | Ref. |
II | 15 (42.8%) | 24 (64.9%) | 0.89 | 1.09 (0.27–4.38) | |
III | 14 (40%) | 6 (16.2%) | 0.076 | 4.08 (0.86–19.37) | |
IV | 2 (5.7%) | 0 | 0.22 | NA | |
Type of Cancer | Tubular | 5 (14.3%) | 3 (8.1%) | Ref. | Ref. |
Ductal | 16 (45.7%) | 16 (43.2%) | 0.53 | 0.60 (0.12–2.94) | |
Medullary | 4 (11.4%) | 5 (13.5%) | 0.46 | 0.48 (0.06–3.35) | |
Lobular | 10 (28.6%) | 10 (27%) | 0.55 | 0.60 (0.11–3.21) | |
Mucinous | 0 | 3 (8.1%) | 0.15 | NA | |
Genotype | Negative (−) | 0 | 61 (96.8%) | < 0.001 | NA |
HPV-18 | 18 (45%) | 1 (1.6%) | Ref. | Ref. | |
HPV-16 | 15 (37.5%) | 0 | 0.58 | NA | |
HPV-33 | 4 (10%) | 0 | 0.85 | NA | |
HPV-11 | 2 (5%) | 1 (1.6%) | 0.17 | 0.11 (0.005–2.55) | |
HPV-6 | 1 (2.5%) | 0 | 0.44 | NA |