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Fig. 3 | BMC Cancer

Fig. 3

From: Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients

Fig. 3

Age-related correlation of apoptosis (%) and BACH2 mRNA expression from healthy donors. Apoptosis decreases with age in both CD4+ T-cells and CD19+ B-cells (a and c). BACH2 downregulation correlated with apoptosis in function of age in CD19+ B cells and CD4+ T-cells (b and d). (Number of sample: CD4+: n = 15, CD19+: n = 15). The percentage of apoptosis was calculated using the difference in the percentage of cells (CD4+ or CD19+) expressing annexin-V after 24 h or 0 h of etoposide treatment

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