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Table 1 Cases reported in literature showing the e6a2 transcript

From: A rare BCR-ABL1 transcript in Philadelphia-positive acute myeloid leukemia: case report and literature review

Diagnosis

Sex/age

Coexpression of other transcripts

Other molecular alterations

Treatment

References

CP - CML

M/41

  

BMT

Hochhaus et al. [2]

CP - CML

M/50

  

IFN-Ara C-- > BMT

Dupont et al. [30]

BC - CML

M/65

  

Imatinib

Schultheis et al. [6]

CP - CML

M/76

  

IFN

Colla et al. [31]

CML secondary to CMML

F/64

 

t(11;16)

Imatinib

Hayette et al. [32]

CP - CML

M/37

e1a2

 

Imatinib

Roti et al. [16]

Acute basophilic leukemia

M/71

  

Imatinib-Dauno-Ara C

Gregoire et al. [33]

ALL

F/29

  

G MALL 7/03-Imatinib-- > BMT

Burmeister et al. [34]

CP - CML

M/43

  

Imatinib

Breccia et al. [35]

AML

F/53

  

Imatinib-Ida-Ara C

-- > BMT-Dasatinib

Ritchie et al. [22]

AML (M7)

F/53

 

del(18)(p10)

Imatinib-Ida-Ara C

-- > Dasatinib-BMT

Corm et al. [23]

CP - CML

M/48

  

Imatinib-- > Dasatinib

Schnittger et al. [36]

CP - CML

M/48

 

t(7;9), ins(22;9)

Imatinib-- > BMT

Vefring et al. [17]

AP - CML

M/42

  

Imatinib

-- > BMT-Dasatinib

Vefring et al. [17]

CP - CML

M/67

  

Imatinib

Popovici et al. [26]

CP - CML

F/18

  

Imatinib

Torres et al. [37]

AP - CML

M/57

 

trisomy 8

Imatinib

Beel et al. [18]

CP - CML

M/36

e1a2

 

Imatinib-Nilotinib

-- > BMT

Langabeer et al. [15]

AP - CML

M/51

  

Imatinib-- > BMT

Rohon et al. [19]

BC – CML

M/48

  

Dasatinib

Zagaria et al. [14]

AML (M4)

F/55

  

Mitox-Ara C-Imatinib

-- > BMT-Dasatinib-DLI

Harada et al. [21]

BC - CML

F/48

 

trisomy and tetrasomy 8

Dauno-Ara c-Imatinib

-- > BMT

Crampe et al. [20]

AML secondary to CMML

M/58

 

DNMT3A RUNX1 SUZ12

3 + 7-Dasatinib-Nilotinib

Yao et al. [25]

AML secondary to myelofibrosis

M/80

 

JAK2-V617F

Hydroxyurea-valproic acid

Dasatinib-Imatinib

Brattas et al. [38]