TY - JOUR AU - Mechera, Robert AU - Soysal, Savas D. AU - Piscuoglio, Salvatore AU - Ng, Charlotte K. Y. AU - Zeindler, Jasmin AU - Mujagic, Edin AU - Däster, Silvio AU - Glauser, Philippe AU - Hoffmann, Henry AU - Kilic, Ergin AU - Droeser, Raoul A. AU - Weber, Walter P. AU - Muenst, Simone PY - 2019 DA - 2019/01/08 TI - Expression of RET is associated with Oestrogen receptor expression but lacks prognostic significance in breast cancer JO - BMC Cancer SP - 41 VL - 19 IS - 1 AB - The Rearranged during Transfection (RET) protein is overexpressed in a subset of Estrogen Receptor (ER) positive breast cancer, with both signalling pathways functionally interacting. This cross-talk plays a pivotal role in the resistance of breast cancer cells to anti-endocrine therapies, and RET expression is assumed to correlate with poor prognosis based on findings in small patient cohorts. The aim of our study was to investigate the impact of RET expression on patient outcome in human breast cancer. SN - 1471-2407 UR - https://doi.org/10.1186/s12885-018-5262-0 DO - 10.1186/s12885-018-5262-0 ID - Mechera2019 ER -