SOURCE | AGE (YEARS) | HISTOLOGY | INVOLVED EOMs | TREATMENTS | OUTCOMES | SURVIVAL |
---|---|---|---|---|---|---|
Wintersteiner H, [7] | 58 | NS | Right MR, IR | NS | NS | NS |
Bedford and Daniel PD, [8] | 72 | NS | All EOMs Bilaterally | NT | NS | 12 Days |
Ashton N, [9] | 58 | UNDIFFERENTIATED | NS | Wide Excision | NS | 2 Years and 6 Months |
49 | UNDIFFERENTIATED | NS | NS | NS | 6 Years | |
Stephen L, [10] | NS | NS | MR | Excision of the Mass | NS | NS |
Thomas A, [11] | 40 | PD | Left LR | RT + CHT | Growth on the lateral aspect completely regressed, no eyeball movement restriction. | NS |
Cuttone JM, [12] | 62 | NS | Left LR | NS | NS | NS |
Mortada A, [13] | 56 | NS | Right LR | CHT + RT (40 Gy) | NS | 3 Years |
55 | NS | Left MR | CHT + RT (40 Gy) | NS | 3 Years | |
53 | UNDIFFERENTIATED | Left SR | CHT + RT (40 Gy) | NS | 3 Years | |
Weiss R, [14] | 66 | Lobular | Left MR | NS | NS | NS |
57 | Lobular | Left SR, LR | NS | NS | NS | |
Citrin referred by Ashton N | NS | NS | Right LR | NS | NS | NS |
Atlas SW, [15] | NS | NS | Left MR | NS | NS | NS |
NS | NS | LR Bilaterally | NS | NS | NS | |
Slavin ML, [16] | 65 | NS | Right SO | RT (30Gy) | Subjective Diplopia and Objective Ophthalmoplegia abated within three months. | NS |
Goldberg RA, [17] | NS | NS | NS | NS | NS | NS |
NS | NS | NS | NS | NS | NS | |
Capone A, [18] | 71 | NS | MR and LR Bilaterally | Refused | NS | 23 Months |
Glazer LC, [19] | 64 | NS | Right MR, Left MR, LR | Tamoxifen + RT (35Gy) + CHT | No response, more advanced periocular infiltration bilaterally, metastases to multiple body sites. | NS |
Van der Herjden A, [20] | 47 | Lobular | Right IR and IO | NS | NS | NS |
Toller KK, [21] | 47 | Lobular | All EOMs Bilaterally | Right Anterior Orbitotomy. RT and CHT refused. | Unchanged | 9 Months |
Lacey B, [4] | NS | Lobular | MR and IR Bilaterally | NS | NS | NS |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
Wallace DK, [22] | 79 | NS | Left MR | Orbital Surgery | No diplopia in primary gaze or reading position. | NS |
Lell M, [23] | 63 | Lobular | MR, SR and SO Bilaterally | NS | NS | NS |
Fenton S, [24] | 53 | NS | LR | RT | Full recovery?? | NS |
Spitzer SG, [25] | 75 | PD | All EOMs Bilaterally | CHT + RT (30 Gy) + Letrozole | Improvement in ocular motility except for limited abduction. | NS |
Peckham EL, [26] | 52 | PD | All EOMs Bilaterally | NS | NS | NS |
Luneau K, [27] | 45 | NS | NS | NS | NS | NS |
Kouvaris JR, [28] | 50 | Lobular | All EOMs bilaterally. | RT (47.5 Gy) + Anastrozole + CHT (vinorelbine and mitomycin) + Local Hyperthermia. | Diplopia partial amelioration. | 13 Months. |
Milman T, [29] | 83 | Ductal | Right LR, MR, SR; | Letrozole | Partial improvement in ocular motility. | NS |
Left IO, IR | ||||||
Valenzuela AA, [30] | NS | NS | NS | NS | NS | NS |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
Murthy R, [31] | 61 | Lobular | Right SR, LR, IR; | RT (54 Gy) + Tamoxifen | Complete resolution at TC/PET, improvement of the ocular motility and resolution of diplopia but mild bilateral ptosis. | NS |
Left SR | ||||||
Wiggings RE, [32] | 49 | NS | Right IR | RT + CHT | Partial Improvement | 11 months |
45 | NS | Four Recti Bilaterally Right SO | RT + CHT | Partial Improvement | 8 months | |
Magliozzi P, [33] | NS | Undifferentiated | IR | NS | NS | NS |
Sharma V, [34] | 43 | Ductal | IR, LR | RT | Improvement | NS |
Khan NA, [35] | NS | Ductal | Right LR; | Whole Brain RT | Partial Response | Alive |
Left IR, LR | ||||||
Amer NM, [36] | 66 | Ductal | Four Recti Unilaterally | Anastrozol + RT (35–40 Gy) | NS | NS |
Pierson TM, [37] | NS | NS | NS | NS | NS | NS |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
NS | NS | NS | NS | NS | NS | |
Homer N, [38] | 47 | Lobular | MR | NS | NS | NS |
63 | Lobular | NS | NS | NS | NS | |
67 | Lobular | MR, LR | NS | NS | NS | |
68 | Not biopsied | Right LR, IR | NS | NS | NS | |
64 | Lobular | Rectus Muscle | NS | NS | NS | |
Current Study | 51 | Ductal | IR | RT (40 Gy) + Fulvestrant+Palbociclib. | Total regression of the orbital lesion at PET/TC without improvement in eyesight. | Alive |