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Table 4 Results of multivariate analysis of overall survival in patients with mCRC

From: Decreased mean platelet volume predicts poor prognosis in metastatic colorectal cancer patients treated with first-line chemotherapy: results from mCRC biomarker study

Variables HR 95%CI P-value
Gender 1.307 0.932–1.833 0.121
MPV (≥ 9.75 fL versus < 9.75 fL) 1.117 0.752–1.658 0.584
WBC 1.589 1.193–2.116 0.002
ANC 0.679 0.470–0.980 0.038
Hemoglobin (≤120 × 109/L vs.>120 × 109/L) 0.809 0.548–1.193 0.285
PLT 0.995 0.991–1.000 0.038
PCT 2.470 0.237–25.702 0.449
NLR 0.921 0.749–1.132 0.436
PLR 1.007 1.003–1.012 0.002
Efficacy 1.582 1.311–1.909 0.000
  1. All variables with a p-value lower than 0.1 in univariate analysis were included in a multivariate statistical analysis