Table 1 Summary of the studies included in the systematic review and meta-analysis
From: Prophylactic cranial irradiation in small cell lung cancer: a systematic review and meta-analysis
Study | Age | Gender (male %) | Brain scan | Complete Response (%) | Extent of disease | Median FU (year) | PCI schedule (Gy/fraction) | N. of patients | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Â | PCI | No PCI | Â | Â | Â | ||
| Â | PCI | No PCI | PCI | No PCI | Â | PCI | No PCI | LD % | ED % | LD % | ED % | Â | Â | Â |
Takahashi et al., 2017 | 69 (43–83) | 69 (37–86) | 84 | 88 | yes | 15 | 14 | 0 | 100 | 0 | 100 | 1 | 25/10 | 224 |
Schild et al., 2012 | 63 (34–79) | 63 (37–80) | 57 | 60 | no | NC | NC | 73 | 27 | 31 | 69 | 6 | 30/15; 25/10 | 739 |
Slotman et al., 2007 | 63 (37–75) | 63 (39–75) | 68 | 57 | no | NC | NC | 0 | 100 | 0 | 100 | 0.8 | 20–30/5–12 | 286 |
Laplanche et al., 1998 | 58 ± 8 | 57 ± 9 | 89 | 92 | yes | 100 | 83 | 17 | 86 | 14 | 5 | 24–30/8–15 | 211 | |
Gregor et al., 1997 | 60 (37–79) | 61 (28–76) | 64 | 62 | no | 100 | 100 | 0 | 100 | 0 | 42 | 8–38/1–18 | 314 | |
Arriagada et al., 1995 | 56 ± 9 | 57 ± 8 | 88 | 86 | yes | 100 | 83 | 17 | 79 | 21 | 8.3 | 24/8 | 294 | |
Ohonoshi et al., 1993 | 62 (43–75) | 66 (45–79) | 65 | 83 | yes | 100 | 61 | 39 | 70 | 30 | 7.5 | 40/20 | 46 | |