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Table 2 Prognostic significance of the 16 selected genes in the HNC patients

From: Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses

No. Gene P -value Hazard ratio (CI) Pathway
4 IGF1R 0.03497 1.57 (1.03–2.41) Focal adhesion HIF-1 signaling pathway PI3K-Akt signaling pathway Pluripotency of stem cells
3 VEGFA 0.14780 1.31 (0.91–1.88) Focal adhesion HIF-1 signaling pathway PI3K-Akt signaling pathway
2 LAMC2 0.00228 1.97 (1.26–3.07) Focal adhesion PI3K-Akt signaling pathway
2 ITGA6 0.00514 1.76 (1.10–2.64) Focal adhesion PI3K-Akt signaling pathway
2 ITGB1 0.01010 1.80 (1.14–2.83) Focal adhesion PI3K-Akt signaling pathway
2 ITGB4 0.01463 1.57 (1.09–2.27) Focal adhesion PI3K-Akt signaling pathway
2 LAMA3 0.01549 1.69 (1.10–2.60) Focal adhesion PI3K-Akt signaling pathway
2 IL6 0.01611 1.57 (1.08–2.28) HIF-1 signaling pathway PI3K-Akt signaling pathway
1 DDIT4 0.00002 2.45 (1.61–3.72) PI3K-Akt signaling pathway
1 JARID2 0.00212 1.91 (1.26–2.91) Pluripotency of stem cells
1 SLC2A1 0.00421 2.17 (1.26–3.73) HIF-1 signaling pathway
1 ENO2 0.00447 1.69 (1.17–2.44) HIF-1 signaling pathway
1 FZD10 0.03798 1.71 (1.02–2.87) Pluripotency of stem cells
1 MYL9 0.07662 0.65 (0.41–1.05) Focal adhesion
1 FLNB 0.12240 1.33 (0.92–1.93) Focal adhesion
1 SGK1 0.03847 1.64 (1.02–2.63) PI3K-Akt signaling pathway
  1. CI confidence intervals