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Table 7 SNP–SNP interaction models analyzed by the MDR method

From: Single nucleotide polymorphism in the 3′ untranslated region of LPP is a risk factor for lung cancer: a case-control study

Model Training Bal. Acc. Testing Bal. Acc. CVC OR (95% CI) p
rs1064607 0.533 0.509 6/10 1.31 (0.96–1.79) 0.080
rs1064607, rs2378456 0.539 0.513 10/10 1.37 (1.01–1.87) 0.042
rs1064607, rs3796283, rs2378456 0.545 0.498 10/10 1.43 (1.05–1.93) 0.022
  1. MDR multifactor dimensionality reduction, Bal. Acc. Balanced accuracy, CVC Cross–validation consistency, OR odds ratio, 95% CI 95% confidence interval. p values were calculated using χ2 tests
  2. Bold indicates statistical signifcance (p < 0.05)