Table 6 Relationship of lymphatic metastatic status with 3′UTR polymorphisms in lung cancer patients adjusted by gender and age
SNP ID | Model | Genotype | Non-Metastasis | Metastasis | Adjusted analysis | Crude analysis | ||
|---|---|---|---|---|---|---|---|---|
OR (95%CI) | p | OR (95%CI) | p | |||||
rs9876 | Allele | G | 121 (48.0%) | 216 (55.4%) | 1.00 | 0.068 | ||
A | 131 (52.0%) | 174 (44.6%) | 0.74 (0.54–1.02) | |||||
Codominant | G/G | 31 (24.6%) | 55 (28.2%) | 1.00 | 0.059 | 1.00 | ||
A/G | 59 (46.8%) | 106 (54.4%) | 1.01 (0.59–1.74) | 1.01 (0.59–1.74) | 0.065 | |||
A/A | 36 (28.6%) | 34 (17.4%) | 0.52 (0.28–1.00) | 0.53 (0.28–1.01) | ||||
Dominant | G/G | 31 (24.6%) | 55 (28.2%) | 1.00 | 0.460 | 1.00 | 0.480 | |
A/G-A/A | 95 (75.4%) | 140 (71.8%) | 0.83 (0.49–1.38) | 0.83 (0.50–1.39) | ||||
Recessive | G/G-A/G | 90 (71.4%) | 161 (82.6%) | 1.00 | 0.017 | 1.00 | 0.019 | |
A/A | 36 (28.6%) | 34 (17.4%) | 0.52 (0.30–0.89) | 0.53 (0.31–0.90) | ||||
Log-additive | – | – | – | 0.73 (0.53–1.01) | 0.058 | 0.74 (0.53–1.02) | 0.063 | |