Single nucleotide polymorphism in the 3′ untranslated region of LPP is a risk factor for lung cancer: a case-control study

Table 2 Basic Information about the candidate SNPs in this study

Gene	SNP ID	Chr: Position	Role	Alleles	Nucleotide change	MAF		O(HET)	E(HET)	p-value for HWE	Call rate (%)
Gene	SNP ID	Chr: Position	Role	(minor/major)	Nucleotide change	Cases	Controls	O(HET)	E(HET)	p-value for HWE	Call rate (%)
NR5A2	rs2246209	1:200145533	UTR-3	A/G	2195G > A	0.301	0.313	0.417	0.430	0.553	100%
NR5A2	rs1056426	1:200146403	UTR-3	C/T	3065 T > C	0.225	0.238	0.367	0.363	0.889	99.72%
LPP	rs1064607	3:188595672	UTR-3	C/G	3405G > C	0.405	0.365	0.453	0.463	0.661	99.86%
LPP	rs3796283	3:188602952	UTR-3	G/A	10684A > G	0.447	0.414	0.474	0.485	0.674	99.86%
LPP	rs2378456	3:188603007	UTR-3	C/G	10739C > G,	0.473	0.453	0.483	0.496	0.608	99.01%
TNS3	rs3750163	7:47317510	UTR-3	A/G	164G > A	0.087	0.079	0.148	0.146	1.000	100%
TNS3	rs9876	7:47315291	UTR-3	A/G	2383G > A	0.475	0.487	0.464	0.500	0.154	99.86%

SNP single nucleotide polymorphism, MAF minor allele frequency, O(HET) observed heterozygosity, E(HET) expected heterozygosity, HWE Hardy-Weinberg equilibrium. p values were calculated with Pearson′s χ² tests; p < 0.05 indicates statistical significance

ISSN: 1471-2407