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Table 4 Baseline characteristics of the patients with advanced NPC stratified by NLR

From: Prognostic value of neutrophil-to-lymphocyte ratio in advanced nasopharyngeal carcinoma: a large institution-based cohort study from an endemic area

  No. of patients (%) stratified by NLR  
Characteristic ≤ 2.50 (n = 813) > 2.50 (n = 737) P value
Age    0.222
  ≤ 45 404 (49.7) 343 (46.6)  
  > 45 409 (50.3) 394 (53.4)  
Sex    0.034
 Male 575 (70.7) 557 (75.6)  
 Female 238 (29.3) 180 (24.4)  
T stage    0.001
 T1 110 (13.5) 80 (10.9)  
 T2 151 (18.6) 114 (15.5)  
 T3 418 (51.4) 378 (51.3)  
 T4 134 (16.5) 165 (22.4)  
N stage    0.015
 N0 106 (13.0) 84 (11.4)  
 N1 485 (59.7) 443 (60.1)  
 N2 132 (16.2) 94 (12.8)  
 N3 90 (11.1) 116 (15.7)  
Overall stage    < 0.001
 II 189 (10.9) 143 (19.4)  
 III 316 (38.9) 341 (46.3)  
 IVA-B 396 (48.7) 253 (34.3)  
Family history    0.574
 No 575 (70.7) 531 (72.0)  
 Yes 238 (29.3) 206 (28.0)  
Smoking history    0.402
 No 496 (61.0) 465 (63.1)  
 Yes 317 (39.0) 272 (36.9)  
Drinking history    0.247
 No 720 (88.6) 638 (86.6)  
 Yes 93 (11.4) 99 (13.4)  
Treatment strategy    0.779
 RT 89 (10.9) 76 (10.3)  
 CCRT alone 316 (38.9) 278 (37.7)  
 NACT+CCRT 408 (50.2) 383 (52.0)  
  1. Abbreviation: NLR neutrophil-to-lymphocyte ratio, CCRT concurrent chemoradiotherapy, NACT neoadjuvant chemotherapy, RT radiotherapy