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Table 1 Prehabilitation interventions

From: Multimodal prehabilitation in colorectal cancer patients to improve functional capacity and reduce postoperative complications: the first international randomized controlled trial for multimodal prehabilitation

Prehabilitation randomized controlled trial scheme
  Preoperative Operation Postoperative
Weeks −5 −4 −1 0 4 8 52
  Before start Baseline (t0) Preoperative (t1) Surgery 30 day follow up (t2) 8 weeks follow up (t3) 1 year follow up (t4)
Gastroenterologist Inform patient
Casemanager Inclusion patient G8 score
Sport physician Informed consent
VO2max
Anaerobic threshold
Exercise-ECG
VO2max
Anaerobic threshold
Exercise-ECG
VO2max
Anaerobic threshold
Exercise-ECG
Physiotherapist 6MWT
Stair climb test
Sit-to-stand test
1-RM
Activity questionnaire
Fried Frailty Score
6MWT
Stair climb test
Sit-to-stand test
Activity questionnaire
6MWT
Stair climb test
Sit-to-stand test
Activity questionnaire
6MWT
Stair climb test
Sit-to-stand test
Activity questionnaire
Dietician Food diary Height, weight
Weight loss %a
Anthropometry
Hand grip strength
PG-SGA
Food diary
Height, weight
Weight loss %a
Anthropometry
Hand grip strength
PG-SGA
Height, weight
Weight loss %a
Hand grip strength
PG-SGA
Height, weight
Weight loss %a
Wrist/abdominal/
Hand grip strength
PG-SGA
Psychologist Intake
Coping with anxietyc
Anesthesiologist Preoperative screeningb ERASb
Surgeon ERAS**
Surgical resident Outpatient data
Researcher HRQoL
GAD-7
PHQ-9
HRQoL
GAD-7
PHQ-9
30-day morbidity and mortality HRQoL
GAD-7
PHQ-9
HRQoL
GAD-7
PHQ-9
Mortality
HRQoL
GAD-7
PHQ-9
  1. aweight loss in the past 3–6 months. bFollowing Enhanced Recovery After Surgery (ERAS) guidelines. cwhen indicated, as stated in the protocol