Table 3 Uni- and multi-variable Cox regressions of factors associated with biochemical recurrence

Age

1.03

(1.01–1.06)

0.015

Preop PSA

1.02

(1.01–1.03)

< 0.001

Year of treatment

1.10

(1.02–1018)

0.012

 ≤6

REF

REF

 3 + 4

3.36

(2.00–5.64)

< 0.001

2.86

(1.68–4.88)

< 0.001

 4 + 3

7.21

(4.13–12.60)

< 0.001

3.88

(2.12–7.07)

< 0.001

 ≥8

13.75

(7.96–23.74)

< 0.001

7.97

(4.38–14.51)

< 0.001

 pT2

REF

REF

 pT3a

3.12

(2.06–4.73)

< 0.001

2.28

(1.48–3.52)

< 0.001

 pT3b & pT4^a

7.37

(4.89–11.12)

< 0.001

3.07

(1.93–4.90)

< 0.001

 Involvment of lymph nodes

8.84

(4.57–17.12)

< 0.001

3.42

(1.70–6.91)

< 0.001

 focal

1.10

(0.63–1.92)

0.742

0.86

(0.49–1.50)

0.586

 extensive

3.80

(2.13–6.77)

< 0.001

2.62

(1.40–4.90)

0.003

 focal

2.59

(1.62–4.14)

< 0.001

 extensive

2.73

(1.46–5.08)

0.002

 focal

2.60

(1.40–4.84)

0.003

 extensive^b

1.45

(0.46 – 4.58)

0.525

 focal

1.55

(0.21–10.98)

0.67