Table 1 Demographics, preoperative and pathological data
Total | Evaluated | Lost to FU | p-value | ||||
|---|---|---|---|---|---|---|---|
n = 530 | c | n = 77 | |||||
Follow-up (months) - median (IQR) | 92 | (87–99) | 47 | (29–87) | |||
Preoperative data | |||||||
Age (years) - median (IQR) | 63 | (58–68) | 63 | (59–68) | 61 | (56–66) | 0.028 |
Preoperative PSA - median (IQR) | 6.4 | (4.8–9.0 | 6.6 | (4.9–9.0) | 6.0 | (4.7–9.2) | 0.628 |
cT stage | 0.019 | ||||||
T1 (a,b,c) | 199 | (38%) | 175 | (39%) | 24 | (31%) | |
T2a | 106 | (20%) | 82 | (18%) | 24 | (31%) | |
T2b | 155 | (29%) | 136 | (30%) | 19 | (25%) | |
T2c | 52 | (10%) | 48 | (11%) | 4 | (5%) | |
T3 | 11 | (2%) | 9 | (2%) | 2 | (3%) | |
unknown | 7 | (1%) | 3 | (1%) | 4 | (5%) | |
D’Amico risk group | 0.005 | ||||||
low | 225 | (42%) | 205 | (45%) | 20 | (26%) | |
intermediary | 196 | (37%) | 152 | (34%) | 44 | (57%) | |
high | 97 | (18%) | 85 | (19%) | 12 | (16%) | |
unknown | 12 | (2%) | 11 | (2%) | 1 | (1%) | |
Nerve sparing | 0.471 | ||||||
unilateral | 13 | (2%) | 12 | (3%) | 1 | (1%) | |
bilateral | 498 | (94%) | 429 | (95%) | 69 | (90%) | |
unknown | 19 | (4%) | 12 | (3%) | 7 | (9%) | |
Pathological results | |||||||
Pathological Gleason Score | 0.005 | ||||||
≤ 6 | 214 | (40%) | 171 | (38%) | 43 | (56%) | |
3 + 4 | 178 | (34%) | 159 | (35%) | 19 | (25%) | |
4 + 3 | 73 | (14%) | 64 | (14%) | 9 | (12%) | |
≥ 8 | 58 | (11%) | 55 | (12%) | 3 | (4%) | |
unknown | 7 | (1%) | 4 | (1%) | 3 | (4%) | |
pT stage | 0.004 | ||||||
pT2 | 385 | (73%) | 321 | (71%) | 64 | (83%) | |
pT3a | 80 | (15%) | 75 | (17%) | 5 | (6%) | |
pT3b | 56 | (11%) | 52 | (11%) | 4 | (5%) | |
pT4 | 2 | (0%) | 2 | (0%) | 0 | (0%) | |
unknown | 7 | (2%) | 3 | (1%) | 4 | (5%) | |
Involvment of lymph nodes | 13 | (2%) | 12 | (3%) | 1 | (1%) | 0.483 |
Positive surgical margins | |||||||
Apical | |||||||
focal | 53 | (10%) | 43 | (9%) | 10 | (13%) | 0.194 |
extensive | 19 | (4%) | 19 | (4%) | 0 | (0%) | 0.054 |
Posterolateral | |||||||
focal | 44 | (8%) | 39 | (9%) | 5 | (6%) | 0.604 |
extensive | 20 | (4%) | 18 | (4%) | 2 | (3%) | 0.454 |
Base | |||||||
focal | 26 | (5%) | 22 | (5%) | 4 | (5%) | 0.840 |
extensive | 7 | (1%) | 7 | (2%) | 0 | (0%) | na* |
Bladder neck | |||||||
focal | 3 | (1%) | 2 | (0%) | 1 | (1%) | na* |
extensive | 0 | (0%) | 0 | (0%) | 0 | (0%) | na* |